Multimodal Imaging of Punctate Outer Retinal Toxoplasmosis
DOI:
https://doi.org/10.62856/djcro.v7.39Keywords:
Chorioretinitis, pediatrics, PORT, recurrence, toxoplasmosisAbstract
We present multimodal imaging of a unique case of ocular toxoplasmosis in a young girl, marked by recurring macular lesions despite treatment and prophylaxis, progressing unusually to punctate outer retinal toxoplasmosis. An eleven-year-old girl, without significant medical history, presented with blurred vision and floaters. Initial assessment showed active macular chorioretinitis in her left eye, inactive scarring in her right eye, and positive IgG but negative IgM toxoplasmosis serologies. Treatment included intravitreal clindamycin, oral azithromycin, and prednisone for her right eye, followed by trimethoprim/sulfamethoxazole (TMP-SMX) prophylaxis. Recurrence in the right eye led to retreatment with clindamycin and TMP-SMX. Recurrences continued and punctiform gray-white lesions in her right eye's retina appeared. These were localized into the outer nuclear layer on OCT with signal hypertransmission and were hypoautofluorescent. Low immunoglobulin levels were identified, suggesting that conventional treatment and prophylaxis might be inadequate in patients with hypogammaglobulinemia.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
The Contributor assigns to Duke, during the full term of copyright and any extensions or renewals, all copyright in and to the Manuscript, and all rights therein, including but not limited to the right to publish, republish, transmit, sell, distribute and otherwise use the Manuscript in whole or in part in electronic editions of the DJCRO and in derivative works throughout the world, in all languages and in all media of expression now known or later developed, and to license or permit others to do so. "Manuscript" means the article submitted by the Contributor for publication in the DJCRO (including any embedded rich media) and all subsequent versions. The definition of Manuscript does not extend to any supporting information submitted with or referred to in the Manuscript ("Supporting Information"). To the extent that any Supporting Information is submitted to the DJCRO, Duke is granted a perpetual, non-exclusive license to publish, republish, transmit, sell, distribute and otherwise use this Supporting Information in whole or in part in electronic and print editions of the DJCRO and in derivative works throughout the world, in all languages and in all media of expression now known or later developed, and to license or permit others to do so. If the Manuscript was shared as a preprint, the Contributor grants to Duke exclusivity as to any rights retained by the Contributor in the preprint.
Reproduction, posting, transmission or other distribution or use of the final Manuscript in whole or in part in any medium by the Contributor as permitted by this Agreement requires a citation to the DJCRO suitable in form and content as follows: (Contributor(s), Title of Manuscript, Journal Title, Journal Volume, Copyright© [year], Digital Object Identifier [DOI] link to final Manuscript). Links to the final article on the DJCRO website are also encouraged where appropriate.
